Start spreading the news that New York City doesn't run New York State. Although the city government is formidable and critical to the safe and prosperous functioning of the nation's great metropolis, New York State has a significant government of its own. Businesses throughout the state must have state-level licenses and sometimes many of them. From retailers, auto mechanics and physicians alike should expect to file forms and respect the Empire State's authority.
In New York, graphic design and online sales, or e-commerce are common home-based businesses. People looking for flexible lifestyles or just to work from home can usually set up these businesses easily. While in many cities including Los Angeles and New York, only standard business licensing requirements apply, numerous cities and counties require Home Occupation Permits for home-based businesses.