Anyone who has ever had their flu or cold eased by Vapo-Rub has enjoyed a little piece of Greensboro on their chest. Vicks is just one of the major corporations that took hold in Greensboro as the town industrialized. Today, Greensboro has a significant, established economy with serious transportation, manufacturing, shipping, education, and hospitality sectors. Like most North Carolina cities, Greensboro has a number of local business regulations requiring somewhat involved licensing and permitting. In many cases, residents must apply in-person and interact with city officials in order to get their businesses approved.